Intraperitoneal injections in mice are typically administered in which anatomical area?

Intraperitoneal injections in mice are typically administered in which anatomical area?

• A. Lower right quadrant near midline
• B. Left forelimb muscle
• C. Subcutaneous tissue in scruff
• D. The tail vein

Answer: (A)

Intraperitoneal injections deliver fluid into the peritoneal cavity, so the injection site is chosen to access that space with minimal risk to internal organs. The lower right quadrant near the midline is used because it provides a relatively safe access point to the peritoneal cavity, keeping clear of major organs and vessels that could be injured if injection were made elsewhere. The other options correspond to different routes: subcutaneous tissue in the scruff is a subcutaneous route, the left forelimb muscle is intramuscular, and the tail vein is intravenous.

Intraperitoneal injections deliver fluid into the peritoneal cavity, so the injection site is chosen to access that space with minimal risk to internal organs. The lower right quadrant near the midline is used because it provides a relatively safe access point to the peritoneal cavity, keeping clear of major organs and vessels that could be injured if injection were made elsewhere. The other options correspond to different routes: subcutaneous tissue in the scruff is a subcutaneous route, the left forelimb muscle is intramuscular, and the tail vein is intravenous.